Kailzie was a peel tower which was ultimately replaced by a new house in the late 17th or early 18th century. Neither building remains.

The lands of Hop-Kailzie are mentioned in a document from 1259 referring to the tenants of Sir Robert of Hop-Kailzie. Archibald and Clement of Hop-Kailzie were both listed as jurors in court documents from 1262. The manor of Wester Hop-Kailzie is first specifically mentioned in a charter of 1305, when it was in the possession of William of Hop-Kailzie who had pledged allegiance to Edward I of England in 1296.

At some point in the 14th century the lands of Hop-Kailzie seem to have been split into Easter and Wester Hopkailzie. In 1465 Easter Hopkailzie became known as Cardrona and Wester Hopkailzie became known as Kailzie.

In the 17th century a doocot was built to provide the castle with food, and it is all that now remains.